Diisopropyl Ether Isopropyl Ether Solvent CAS 108-20-3
Product Overview
Chemical Name: Isopropyl Ether (also known as Diisopropyl Ether, DIPE)
CAS Number: 108-20-3
Molecular Formula: C₆H₁₄O
Molecular Weight: 102.18 g/mol
Appearance: Colorless, clear liquid with a characteristic ether-like odor
Boiling Point: 68-69°C (154-156°F)
Flash Point: -28°C (-18°F; closed cup)
Isopropyl Ether is a volatile, flammable ether compound widely recognized for its excellent solvent properties. As a mid-polarity solvent, it balances solubility for both organic and slightly polar substances, making it a key material in chemical synthesis, extraction, and industrial cleaning. Its low boiling point and moderate volatility also enable easy recovery in distillation processes, supporting cost-efficiency and sustainability.
Key Properties & Advantages
| Property | Specification | Core Advantage |
| Solubility | Slightly soluble in water (~1.2 g/L at 20°C); miscible with ethanol, acetone, benzene, and most organic solvents | Versatile for dissolving oils, resins, waxes, and organic compounds; compatible with common co - solvents |
| Volatility | Vapor pressure: 16.9 kPa at 20°C; low boiling point (68 - 69°C) | Enables fast evaporation in coating/drying processes; easy separation via distillation |
| Chemical Stability | Stable under normal storage conditions; decomposes slowly in contact with strong acids or peroxides | Reliable for long - term storage (when protected from peroxides); minimal reactivity with most substrates |
| Density (20°C) | 0.725 g/cm³ | Low density reduces transport costs; easy to handle in liquid mixing processes |
| Autoignition Temperature | 443°C (829°F) | Safer than highly flammable solvents (e.g., diethyl ether) in controlled environments |
Typical Applications
Isopropyl Ether’s solvent versatility and volatility make it indispensable across multiple industries:
3.1 Chemical Synthesis & Extraction
Organic Synthesis: Serves as a reaction solvent for Grignard reactions, alkylations, and esterifications. Its low polarity helps control reaction rates and improve product yields for non-polar intermediates.
Liquid-Liquid Extraction: Used to separate organic compounds from aqueous solutions (e.g., extracting pharmaceuticals, pesticides, or flavor compounds from fermentation broths or plant extracts).
Peroxide Production: Acts as a raw material for manufacturing diisopropyl peroxydicarbonate (IPP), a common initiator for polymer synthesis (e.g., polyvinyl chloride, PVC).
3.2 Industrial Cleaning & Coating
Degreasing Agent: Effective for removing oil, grease, and wax from metal parts (e.g., automotive components, machinery) due to its strong solvency for hydrocarbons.
Coating & Adhesive Formulations: Dilutes resins, lacquers, and adhesives to adjust viscosity, ensuring smooth application and fast curing (used in wood coatings, industrial adhesives).
3.3 Laboratory & Analytical Uses
Chromatography Solvent: Employed as a mobile phase component in gas chromatography (GC) and high-performance liquid chromatography (HPLC) for separating organic analytes.
Solvent for Sample Preparation: Dissolves solid samples (e.g., lipids, polymers) for chemical analysis (e.g., Fourier-transform infrared spectroscopy, FTIR).
3.4 Fuel & Energy
Fuel Additive: Mixed with gasoline to improve octane rating and reduce engine knock; also enhances fuel stability during storage.
Safety & Compliance
4.1 Safety Guidelines
Flammability Risk: Highly flammable liquid and vapor; keep away from open flames, sparks, and hot surfaces (use explosion-proof equipment in handling areas).
Peroxide Formation: Can form explosive peroxides when exposed to air, light, or heat over time. Test for peroxides (using starch-iodide paper) before use; discard if peroxides are detected.
Handling Protective Gear: Wear nitrile gloves, chemical splash goggles, and a vapor respirator (N95 or higher) in poorly ventilated spaces. Avoid skin/eye contact (may cause irritation) and inhalation of vapors (can cause dizziness or nausea).
Storage: Store in a cool, dark, well-ventilated area; use airtight, amber glass or HDPE containers. Add a peroxide inhibitor (e.g., hydroquinone) for long-term storage.
4.2 Regulatory Compliance
REACH (EU): Registered under REACH (Registration Number: 01-2119488787-46-xxxx); compliant with restrictions on peroxide impurities.
OSHA (U.S.): Occupational Exposure Limit (OEL): 500 ppm (8-hour TWA); classified as a flammable liquid (NFPA Class IB).
GHS Classification: GHS02 (Flammable Liquid), GHS07 (Irritant), GHS08 (May form explosive peroxides).
ISO Standards: Meets ISO 6353-2 (Reagent grade specifications) for laboratory use.
Technical Data Sheet (TDS) Highlights
| Parameter | Industrial Grade | Reagent Grade | Test Method |
| Purity (min) | 99.0% | 99.5% | Gas Chromatography (GC) |
| Moisture Content (max) | 0.1% | 0.05% | Karl Fischer Titration |
| Peroxide Content (max) | 5 ppm | 1 ppm | Iodometric Titration |
| Acidity (as CH₃COOH, max) | 0.005% | 0.001% | Sodium Hydroxide Titration |
| Non - Volatile Residue (max) | 5 mg/kg | 1 mg/kg | Gravimetry |
Why Choose Our Isopropyl Ether (CAS 108-20-3)?
Low Peroxide Risk: Our product is stabilized with food-grade inhibitors, reducing peroxide formation and ensuring safe use.
Consistent Purity: Batch-to-batch purity control (≥99.0% for industrial grade) minimizes impurities that disrupt processes.
Customized Packaging: Available in 1L, 20L, 200L drums, or ISO tanks for small 实验室 or bulk industrial orders.
Technical Support: Our team provides guidance on peroxide testing, storage, and application optimization (e.g., solvent blending for extraction).
Global Compliance: Meets international standards (REACH, OSHA, ISO) for use in EU, U.S., and Asian markets.
Contact Us
For pricing, samples, or full TDS/COA documentation, reach out to our sales team:
Email: info@anhaochemical.com
Phone: +86 15169355198
Website: https://www.anhaochemical.com/